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Complete Scientific Program



September 5th
Time Type Theme Speaker Room
8:30 - 17:30 SA1 Clinical Pharmacy: New Challenges in Research and Professional Development   Ametista
  SA1.1 Translational Methodologies in Clinical Pharmacy Marcela Carolina Jirón Aliste - Universidad de Chile
8:30 - 17:30 SA2 From Candidate Selection to Proof-of-Concept: Translating Pharmacology into Medicines Opala
  SA2.1 From Candidate Selection to Proof-of-Concept

Oscar Della Pasqua - UCL School of Pharmacy

Frank L. Kloprogge - UCL School of Pharmacy

10:00 - 16:00 SA3 III Brazilian Colloquium on Medicinal Chemistry Ágata
10:00 - 11:00 SA3.1 The Importance of Compound Design in Drug Discovery Arasu Ganesan - University of East Anglia
11:00 - 12:00 SA3.2 Designing library of heterocycles to fight neglected diseases Flávio Emery - FCFRP-USP
14:00 - 15:00 SA3.3 Drug Design strategies in the discovery of PDE7 inhibidors Carmen Gil - Centro de Investigaciones Biológicas-CSIC
15:00 - 16:00 SA3.4 In silico drug repositioning for neglected tropical diseases Carolina Horta de Andrade - UFG
10:00 - 17:30 SA4 Nanobiotechnology: New Strategies for Producing Innovative Medicines Topázio
10:00 - 11:00 SA4.1 Biopharmaceuticals: Translating Science into Innovative Medicines Gary Walsh - University of Limerick
11:00 - 12:00 SA4.2 The Impact of Nanobiotechnology on the Development of New Drug Delivery Systems Silvia Stanisçuaski Guterres - UFRGS
14:00 - 16:00 SA4.3 Round Table: Brazilian NanoBiotechnology

Maria Vitória L. B. Bentley - FCFRP-USP

Thiago Mares Guia - Bionovis

Marcelo Mario Matos Moreira - Anvisa

16:30 - 17:30 SA4.4 Oral Presentations  
8:30 - 19:15 SA5 6th PhytoPharmatech Rubi
8:15 - 8:30   OPENING
8:30 - 9:30 SA5.1 Innovative Bioprocessing Strategies for Phytopharmaceuticals and Agro-Health Products

Sandeep Kale - ICT/Mumbai, India

Chair: Luis Alexandre Pedro de Freitas - USP

10:00 - 11:00 SA5.2


Technical Session 1    

Chair: Osvaldo de Freitas - USP                                                                                            


1)”Development of wound healing dress based on bacterial cellulose biomembrane with propolis” – Torres, E.C. –Unesp/Apis
2) “Chemical composition and antimicrobial activity of different propolis” – Ferreira, N.U.B. et al – USP/Apis
3)“Cytotoxicity assay of highly loaded curcumin-Gelucire® 50/13 and curcuma extracts-Gelucire® 50/13”  Teixeira, CC et al – USP
11:00 - 12:00 SA5.3


Herbal Medicines: Opportunities and Challenges for the Academy and the Brazilian Industry                                                                         

Tania Mari Bellé Bresolin - UNIVALI
13:30 - 15:00 SA5.4


Technical Session 2

Chair: José O. Carrera Junior - UFPa                                                                                             


1) “Arabidaea chica: Chemical and cytotoxic studies of extracts lyophilized and dry for spray dryer” – Gomes, M.R.F. et al - UFPa
2) “The stability of microencapsulated  Chamomilla recutita (L.) extract” Reis, R.A.S.P. et al. - USP
3)  "Encapsulation and agglomeration of herbal compositions by fluidized bed process." Benelli, L. et al. - USP
4) Supercritical extraction of Copaifera langsdorffii leaves" Costa et al - USP
15:00 - 16:00 SA5.5 Technical Session 3                                                                                                           Chair: Tania Bresolin - UNIVALI
1) “Caracterização de Resíduos Agroindustriais de Theobroma cacao L” – Oliveira, K.A. et al - UFPa
2)  “Influence of ethanol concentration in the extractive process of furanocoumarins from Ruta graveolens L.” Arruda, R.L. et al – UFG
3) “Hydrogel of polyacrylamide-co-methyl-cellulose containing extract of Calendula oficinalis L for pressure ulcers treatment” Castro, L.D. et al – UFPa
16:30 - 17:30 SA5.6 Natural Products, neuroprotection and cosmeceuticals: a translational approach

Alberto Carlos Pires Dias - Universidade do Minho        

Chair: José O. Carrera Junior - UFPa

17:30 - 19:00 SA5.7
Round Table  -
Drying of Phytopharmaceuticals
Chair: Osvaldo de Freitas - USP

Tatiane Pereira de Souza - UFAM

Cláudia Souza - USP

Luis Alexandre Pedro de Freitas – USP

19:00 - 19:15   CLOSING  
9:30 - 10:00 COF COFFEE BREAK 1st Floor
12:00 - 14:00 L LUNCH 1st Floor
16:00 - 16:30 COF COFFEE BREAK 1st Floor



September 6th
Time Type Theme Speaker Room
8:30 - 13:00 SA1 Clinical Pharmacy: New Challenges in Research and Professional Development  Ametista

Round Table: Pharmaceutical Education

Leonardo Regis Leira Pereira - FCFRP-USP
Luciano Soares - Univille/ABEF

Armando da Cunha Silva Junior - CAPES/UFMG

Danyelle Cristine Marini - FIMI

Dayde Lane Mendonça - UnB

Mareni Rocha Farias - UFSC

Maria Ondina Paganelli - DAF/MS

Marise Bastos Stevanato – UNAERP/Comissão de Ensino CRF-SP

Orlando Mário Soeiro - Unicamp - DAF/MS

Vania dos Santos - FCFRP-USP/ABEF

8:30 - 16:30 SA2 From Candidate Celection to Proof-of-Concept: Translating Pharmacology into Medicines Opala
  SA2.1 From Candidate Selection to Proof-of-Concept

Oscar Della Pasqua - UCL School of Pharmacy

Frank L. Kloprogge - UCL School of Pharmacy

8:30 - 12:00 SA3 III Brazilian Colloquium on Medicinal Chemistry Ágata
8:30 - 9:30 SA3.1 The next generation bioisosterism

Lidia Moreira Lima - UFRJ

10:00 - 12:00 SA3.2 Workshop Perspectives for Drug Discovery in Brazil Harren Jhoti - Astex Pharmaceuticals
James Bradner - Harvard University
Ian Waddel - Cancer Research UK
8:30 - 12:00 SA4 Nanobiotechnology: New Strategies for Producing Innovative Medicines Topázio
8:30 - 9:30 SA4.1 Challenges in Biopharmaceutical Production Rimenys Junior Carvalho - UFRJ
10:00 - 11:00 SA4.2 Nanostructures based on lipids: New advances and perspectives Benjamin Boyd - Monash University
11:00 - 12:00 SA4.3 Nanotechnology for targeting bloodborne cancer metastasis Michael Mitchell - Koch Institute for Integrative Research, MIT
8:30 - 15:30 SA5 II Alternative in Vitro Assays for Toxicity Testing of Drugs Rubi
8:30 - 9:10 SA5.1 Traditional and new paradigms for risk assessment Silvia Berlanga de Moraes Barros - FCF-USP
Lorena Rigo Gaspar Cordeiro - FCFRP-USP
9:10 - 9:30 SA5.2 Skin corrosion and irritation: achievements of Brazilian model Silvya Stuchi Maria-Engler - FCF-USP
10:00 - 10:30 SA5.3 Safety assessment of hair dyes using 3D skin models Thalita Boldrin Zanoni - FCF-USP
10:30 -11:00 SA5.4 Photo safety assessment of topical raw materials Lorena Rigo Gaspar Cordeiro - FCFRP-USP
11:00 - 11:30 SA5.5
Tridimensional model for neurotoxicity evaluation
Marize Campos Valadares - UFG
11:30 - 12:00 SA5.6 Zebrafish as an experimental model in Toxicology Danielle Palma de Oliveira - FCFRP-USP
14:00 - 14:30 SA5.7 Alternative models for the evaluation of antifungal agents Maria José Soares Mendes Giannini - FCFAR - UNESP
14:30 - 15:10 SA5.8 Challenges and perspectives in research on alternatives to animal testing Monika Shäfer-Korting - Freie Universität - Berlin
15:10 - 15:30 SA5.9 Closing Discussions  
9:30 - 10:00 COF COFFEE BREAK 1st Floor
12:00 - 14:00 L LUNCH 1st Floor




September 6th
Time Theme Speaker Room
20:00 - 20:50 Opening Conference
     Natural Product-Based Drugs: Crossing the Valley of Death in Their Development David Newman - NIH
21:00 COCKTAIL 1st Floor



September 7th
Time Type Theme Speaker Room
8:30 - 9:30 L2 Keys for paving the way to the market in drug discovery Ana Martinez Gil - Centro de Investigaciones Biologicas-CSIC
Chair: Ivone Carvalho
8:30 - 9:30 L3 Biopharmaceuticals: Translating Science into Innovative Medicines Gary Walsh - University of Limerick
Chair: Kamilla Swiech
8:30 - 9:30 L4 Targeting the Epigenome James Bradner - Harvard University
Chair: Mônica Tallarico Pupo
9:30 - 10:30 PS1 COFFEE BREAK/POSTER SESSION 1st Floor
10:30 - 12:30 S1 Paving new strategies targeting Inflamation drug discovery
Chair: Lusiane Maria Bendhack
  S1.1 Translating Disease to Treatment Richard Minshall - University of Illinois, Chicago
S1.2 New trends in anti-inflammatory drugs Eliezer Jesus de Lacerda Barreiro - UFRJ
10:30 - 12:30 S2 The Evolving Role of Biotechnology in Medicine
Chair: Hamilton Cabral and Priscyla Daniely Marcato
  S2.1 Biopharmaceutical development in microbial systems Fernando Araripe Gonçalves Torres - UNB
S2.2 Erythropoietin: From Scientific Development to Industrial Production Ricardo Kratje - Universidad Nacional del Litoral
S2.3 Technique of Micro-Fabricated Technologies for Intracellular Delivery of Biopharmaceuticals by Membrane Disruption Martin P. Stewart - Koch Institute for Integrative Cancer Research, MIT
10:30 - 12:30 S3 Cancer Therapy - New Approaches Toward Innovative Products
Chair: Luciana Biagini Lopes
  S3.1 Fragment-Based Drug Discovery Harren Jhoti - Astex Pharmaceuticals
S3.2 Collaborating with industry to find chemical hits versus difficult oncology targets Ian Waddell - Cancer Research UK
S3.3 Systems pharmacology strategies for anticancer drug discovery based on natural products Leticia Veras Costa Lotufo - USP
12:30 - 14:00 LUNCH 1st floor
14:00 - 16:00 S4 Advances in Pharmaceutical Technology
Chair: Priscyla Daniely Marcato
  S4.1 Lipid nanoparticles as carriers for therapeutic delivery of microRNA-based oligonucleotides Robert Lee - Ohio State University
S4.2 Formation of nanostructures during the digestion of lipid-based formulations - implications and opportunities for nutritional and pharmaceutical delivery Benjamin Boyd - Monash University
S4.3 PET Radiopharmaceuticals in Cancer Imaging and Therapy Monitoring Xiaoyuan Chen - National Institute of Biomedical Imaging and Bioengeneering
14:00 - 16:00 S5 Cannabinoids - Clinical and Pre-Clinical Facts
Chair: Sâmia Regiane Lourenço Joca
  S5.1 Cannabis and Cannabinoids: Ethnobotany, Psychopharmacology, and Therapeutic Potentials Rafael Guimarães dos Santos - FMRP-USP
  S5.2 Mechanisms responsible for the neuropsychiatric effects of cannabidiol Francisco Silveira Guimarães - FMRP-USP
  S5.3 Cannabinoids as pharmacological approaches to modulate seizures and excitotoxicity Fabrício de Araújo Moreira - UFMG
14:00 - 16:00 S6 The Pharmaceutical Sciences Guided by Organic Synthesis
Chair: Giuliano Cesar Clososki
  S6.1 Translating Organic Synthesis into Therapeutic Products Dieter Schinzer - Magdeburg, Germany
S6.2 Synthesis of Cyclic Compounds by Organocatalytic/Multicomponent Reactions Sequence and Photochemical Approaches Márcio Weber Paixão - UFSCAR

Hunting for Biological Activity with Natural and Unnatural Scaffolds

Arasu Ganesan - University of East Anglia
16:00 - 17:00 L5 Innovative Strategies for Enhancing Topical Drug Delivery Renata Fonseca Vianna Lopez - FCFRP-USP
Chair: Priscyla Daniely Marcato
16:00 - 17:00 L6 Cannabis and Epilepsy: Fact from Fiction Ben Whalley - Reading University
Chair: Sâmia Regiane Lourenço Joca
16:00 - 17:00 L7 New Synthetic Tools for Medicinal Chemists: Rapid Preparation of Oxygen- and Nitrogen-Containing Heterocyclic Scaffolds and Chiral Building Blocks Laszlo Kurti - Rice University
Chair: Giuliano Cesar Clososki  
17:00 - 18:00 PS2 COFFEE BREAK/POSTER SESSION 1st Floor
17:00 - 19:00 ABCF Meeting Topázio



September 8th
Time Type Theme Speaker Room
8:30 - 9:30 L8 Mechanism-Based Drug-Disease Modeling Applied to Drug Development and Regulatory Decision Making Stephan Schmidt - University of Florida
Chair: Teresa Dalla Costa
8:30 - 9:30 L9 Emerging applications of ruthenium compounds as modulators of nitric oxide and singlet oxygen by light irradiation. Use against cancer cells. Roberto Santana da Silva - FCFRP-USP
Chair: Norberto Peporine Lopes
8:30 - 9:30 L10 The Powerful Effect of Placebo Oscar Della Pasqua - UCL School of Pharmacy
Chair: Vera Lúcia Lanchote
9:30 - 10:30 PS3 COFFEE BREAK/POSTER SESSION 1st Floor
10:30 - 12:30 S7 Antimicrobial PK/PD
Chair: Teresa Dalla Costa
  S7.1 Translation from bench to bedside in infectious diseases: an example from the ICU George Drusano - University of Florida
S7.2 PKPD-modeling for translation of antibiotic effects Lena Friberg - Uppsala University
S7.3 Importance of Free Tissue Concentrations for PK/PD Modeling of Antimicrobials Teresa Dalla Costa - UFRGS
10:30 - 12:30 S8 Small Bioregulator Molecules
Chair: Roberto Santana da Silva
  S8.1 The Oncogenic properties of the Redox Inflammatory Protein inducible Nitric Oxide Synthase in ER(-) Breast Cancer.  Development of Models for Poor Outcome David Wink - National Cancer Institute
S8.2 Strategies for the photochemical uncaging of bioactive small molecules Peter Ford - UC Santa Barbara
S8.3 Harnessing redox signaling agents for treatment of cancer Katrina Miranda - University of Arizona
10:30 - 12:30 S9 Cosmetics: Going Beyond
Chair: Patricia Maria Berardo Gonçalves Maia Campos
  S9.1 Natural antioxidants and skin protection from UV radiation: a possible claim for sunscreens Silvia Berlanga - FCF-USP
S9.2 EPISKIN and the application of reconstructed human 3D models in toxicology and pharmacology Christian Pellevoisin - Episkin Institute
"Use of in vitro assays to predict clinical efficacy of cosmetics"
Phillipe Masson - EVIC France
12:30 - 14:00 LUNCH 1st Floor
14:00 - 16:00 S10 Infectious disease - The Biology Perspective of Translational Development
Chair: Maria Cristina Nonato
  S10.1 The under exploited potential in drug discovery for neglected diseases in Brazil Lucio Holanda Gondim de Freitas Junior - LNBio
S10.2 Vaccine research, development and innovation in Brazil: a translational science perspective Cristina de Albuquerque Possas - FioCruz
14:00 - 16:00 S11 Young Researchers
Chair: Carolina Patrícia Aires
14:00 - 14:15 S11.1 TL 01 Drug-resistant cancer: is it possible to reverse this process? Evelyn Winter da Silva - Florianópolis/SC
14:15 - 14:30 S11.2 TL 02 Inhibition of cell proliferation, invasion and migration by cardenolides in human lung cancer cell line Fabiana Cristina Geller - Florianópolis/SC
14:30 - 14:45 S11.3 TL 03 Sodium salicylate induces the expression of atf6 transcription factor and endoplasmic reticulum (er) stress responsive genes through an unconventional er stress pathway Fernanda Lins Brandão Mügge - Belo Horizonte/MG
14:45 - 15:00 S11.4 TL 04 Synthesis of thioalkylated bodipys from thiocyanated derivatives: an approach for the development of new fluorophores with diverse optical features Lucas Cunha Dias de Rezende - Ribeirão Preto/SP
15:00 - 15:15 S11.5 TL 05 Drug-like analysis of in-house chemical library Nuria E. Campillo - Madrid/Spain
15:15 - 15:30 S11.6 TL 06 Liposomal voriconazole (vor) formulation for improved ocular delivery Tais Gratieri - Brasília/DF
15:30 - 15:45 S11.7 TL 07 In silico modelling and molecular dynamics of nonclassical major histocompatibility complex class i hla-g protein Thaís Cristine Arns - Ribeirão Preto/SP
15:45 - 16:00 S11.8 TL 08 Distance training course as strategy to training pharmacists on dispensing of drugs Tiago Marques Dos Reis - Ribeirão Preto/SP
14:00 - 16:00 S12 Challenges and Perspectives in Research on aAlternatives to Animal Testing
Chair: Lorena Rigo Gaspar Cordeiro


Skin reconstructed in perspective of alternative methods to animal experimentation

Silvya Stuchi Maria-Engler - FCF-USP
Alternative Test Methods and Integrated Strategies for Ocular Toxicity Investigation 
Marize Campos Valadares - UFG
S12.3 Modeling neurodevelopmental disorders from induced pluripotent stem cells Patrícia Cristina Baleeiro Beltrão Braga - USP
16:00 - 17:00 L11 Recent Collaborations with the Drugs for Neglected Diseases initiative (DNDi) and with Medicines for Malaria Venture (MMV) in the area of Neglected diseases 

Luiz Carlos Dias - UNICAMP      

Chair: Giuliano Cesar Clososki 

16:00 - 17:00 L12 Challenges to establish and run a research group in Brazil that develops a high impact research

Dario Simões Zamboni - FMRP

Chair: Carolina Patrícia Aires

Lessons and Challenges from a Young Medicinal Chemist Point of View

Carolina Horta Andrade - UFG

Chair: Carolina Patrícia Aires

16:00 - 17:00 L13 In-vitro Models for Drug Research - Conventional Drugs and Nanoparticle-Forced Drug Delivery Monika Shäfer-Korting - Freie Universität - Berlin
Chair: Lorena Rigo Gaspar Cordeiro
17:00 - 18:00 PS4 COFFEE BREAK/POSTER SESSION 1st Floor
17:00 - 19:00 AAPS Meeting Topázio



September 9th
Time Type Theme Speaker Room
8:30 - 9:30 L14 Nanotoxicology; Basic Concepts and Recent Findings Hamid Ghandehari - Utah University
Chair: Priscyla Daniely Marcato
8:30 - 9:30 L15 Stereoselectivity in Clinical Pharmacokinetics Vera Lucia Lanchote - FCFRP-USP
Chair: Fernando Barbosa
9:30 - 10:00 COF COFFEE BREAK  1st Floor
10:00 - 12:00 S13 Cancer Therapy - New Technological Approaches
Chair: Hosana Maria Debonsi
  S13.1 Genetic and enviromental factor toward cancer Roger Chammas - USP
S13.2 Molecules involved in sustaining malignant phenotypes of melanoma Enilza Maria Espreafico - FMRP-USP
S13.3 Strategies for Chemical Synthesis of Antitumor Molecules inspired by Redox Centre and Ring Modifications Eufrânio Nunes da Silva Júnior - UFMG
10:00 - 12:00 S14 Natural products - Looking to Bigger Hits
Chair: Eliane Candiani Arantes
  S14.1 Structural similarity between defense peptides and invertebrate neurotoxins permits rational functional design Jan Tytgat - KU Leuven
S14.2 Natural Peptides of Models for Development of Novel Drugs Mário Sérgio Palma - Unesp Rio Claro
S14.3 Rational development of Amblyomin-X, a Kunitz type inhibitor, as a new antitumor agent. Ana Marisa Chudzinski Tavassi  - Instituto Butantan
12:00 - 13:00 CLOSING CEREMONY Rubi






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